Dr Nedic’s opinion about Bioidentical hormones featured in the Longevity magazine
BALANCING YOUR HORMONES FOR IMPROVED HEALTH
“Happiness is not a matter of intensity, but of balance, order, rhythm and harmony,” says Thomas Merton. On this matter, Dr Sly Nedic, an aesthetic and anti-aging practitioner who specialises in genetic testing, hormones and personalised medicine treatments, would be happy to agree. “Hormonal health works as a balance of hormones. What people may not recognize is that, in order to function, hormones talk to one another. There needs to be a balance, a symphony, in order to achieve optimal health,” explains Nedic. It is when this balance is disrupted that we learn how truly fundamental hormones are.
“IT’S PARADOXICAL THAT THE IDEA OF LIVING A LONG LIFE APPEALS TO EVERYONE, BUT THE IDEA OF GETTING OLD DOESN’T APPEAL TO ANYONE.”
– Andy Rooney
Oestrogen dominance is an example of hormone imbalance and can occur in the body for a number of reasons:
- Trans-fatty acid intake;
- Chronic stress;
- Sleep deprivation;
- Fluoridated water;
- Cadmium toxicity;
- Lack of sulphur-containing amino acids;
- Lack of good exercise;
- Environmental xeno-oestrogens;
- Zinc deficiency;
- Progesterone deficiency;
- Magnesium deficiency;
- Testosterone deficiency; or
- Poor genomic detox pathways.
THIS RESULTS IN A NUMBER OF VERY UNPLEASANT SYMPTOMS:
- Irritability/mood swings;
- Irregular periods;
- Heavy menstruation;
- Water retention/bloating;
- Short-term memory loss;
- Weight gain;
- Craving for sweets;
- Uterine fibroids (previously diagnosed);
- Sleep disturbance;
- Breast swelling (all month);
- Fibrocystic breasts (by history);
- A blocker on weight loss;
- Low libido;
- A decrease in metabolism, energy and heat production; and
- Thyroid efficiency blocked by 25% – prone to thyroid disease.
THE IMPACT OF ENVIRONMENTAL TOXINS
Unfortunately, there are xenooestrogens in our environment that can have an impact on our hormone health and result in a state of oestrogen dominance. A few examples are:
- Parabens in make-up;
- Bisfenol A in plastic bottles;
- Pesticides in conventionally grown food;
- The effect of stress on our cortisol levels; and
- PAHs (polycyclic aromatic
- hydrocarbons) when driving to work.
These all interfere with the body’s process of methylation – the process which turns your genes on an off. When you are oestrogen-dominant, different aspects of the body’s methylation process get reassigned to protect the body against the invading toxin – oestrogen – and your whole system goes out of balance.
WHAT YOU NEED TO KNOW ABOUT HORMONE REPLACEMENT THERAPY
“Perimenopausal women are often oestrogen-dominant. When HRT treatment starts, you are often given oestrogen with progestogen (a synthetic form of progesterone). However, this does not foster hormonal balance – instead, it causes a number of health issues,” says Nedic. “Oestrogen must be given with progesterone, and in accordance with individualised amounts of the other hormones, in order for you to maintain a healthy hormone balance.” Dr Pascale Henquin, an integrative anti-aging medical practitioner, adds that one of the first places you have to start when treating hormone health is with the adrenals – and HRT doesn’t factor this in at all. “The adrenals are the foundation on which you will build the rest of your hormonal health.”
WHAT DOES THE RESEARCH SAY?
The most famous HRT study was conducted by the US National Institute for Health, under its Women’s Health Initiative in 1999. It indicated that HRT increased one’s risk of:
- Heart attack by 29%;
- Stroke by 32%;
- Thrombosis by 113%; and
- Breast cancer by 26%.
However, while the first three statistics still hold, a 2016 study suggests that previous research has underestimated the risk of breast cancer by up to 60%. It also reveals that HRT as much as triples the risk of breast cancer in patients.
THE NEW FACTS ARE AS FOLLOWS:
- Women who take HRT to relievethe symptoms of menopause are 2.7 times more likely to develop breast cancer;
- Women who use combined HRT for more than 15 years have 3.27 times the increased risk;
- Around one in 10 women use HRT in their 50s to combat menopausal symptoms such as depression, hot flushes and migraines; and
- There were an estimated 900 000 prescriptions for combined HRT last year in Britain alone.
- The researchers were thorough, drawing data from more than 100 000 women who took part in a 40-year breast cancer study.
Thankfully, there is a safer alternative to HRT.
BIO-IDENTICAL HORMONE REPLACEMENT THERAPY (BHRT): THE BETTER ALTERNATIVE
Nedic explains why personalised, bio-identical HRT is the way of the future: “Bio-identical HRT contains hormones that are chemically identical to those produced by a women’s body. In contrast, conventional HRT is a ‘one-size-fits-all’ approach to the treatment of menopausal symptoms. The fact is that women metabolise oestrogen differently – as individuals – and with conventional HRT this is not taken into account.”
Henquin adds: “I believe that BHRT is the only safe intervention for addressing menopause.”
It is important to note that:
- Women can metabolise oestrogen in both a favourable or an unfavourable way, depending on a number of factors; and
- A woman who metabolises oestrogen unfavourably – when prescribed HRT – will experience medical
Nedic states that the dangerous thing about oestrogen is that it can be metabolised in a way that is DNA-damaging, causing cancer. Happily, we no longer have to guess to what degree a patient can favourably metabolise oestrogen. “We can run a test which tells us the exact genetic profile of each individual, including how they metabolise oestrogen. We can then create a personalised, bio-identical HRT treatment for that individual.”
This can include:
- Bio-identical hormones specific to the individual;
- The correct dose of oestrogen and progesterone for the individual;
- Supplements which manipulate the body into metabolizing oestrogen favourably; and
- Lifestyle changes to ensure that the body metabolises oestrogen favourably
THE FINAL WORD
When navigating the world of HRT, it is advisable to take a holistic and personalised approach, as this will give the best results. We have technology available to us today that can provide us with medication designed to suit our specific needs.
- Know your personal risk of developing breast cancer;
- Find out how you can optimise the way your body processes oestrogen;
- Don’t allow any medical practitioner to sell you a one-size-fits-all approach;
- Empower yourself through healthy lifestyle changes when dealing with any health challenge; and
- Know that a holistic approach to your health is always key in finding a workable solution. Educate yourself by keeping up- to-date with new studies. Your health is ultimately in your own hands.