“we are simply products of our gene-environment”
We are all born with a specific genetic make-up which never changes. However certain environmental factors and diet can influence gene expression in some individuals in a negative or positive way. For example, siblings can eat the same food and one can become diabetic or overweight when the other may not. There is a great variation in the presence of low penetrance gene mutations (SNPs) in humans. These gene mutations in some individuals cause degenerative diseases, premature aging, obesity, cancer, diabetes etc. under the influence of environmental toxicity and other nutritional and life style factors. To put it simply: we are “products of our gene-environment and the food we eat and the toxins we absorb talk directly to our genes all day long.”
By identifying each individual’s genetic make–up with genetic testing, we can recognize which life style and nutritional changes a person needs to apply in order to prevent detrimental diseases. This is what we call Personalized Prevention. In practical terms: gene expression can be changed by using Epigenetic intervention to prevent a disease from manifesting.*
There are two types of genetic testing techniques – Predictive and Preventive.
Predictive Genetic Testing
- Used to detect mutations associated with disorders that appear after birth, often later in life.
- Identify mutations that could increase a person’s risk of developing disorders based on their genetic makeup, such as certain types of cancer.
Preventive Genetic Testing
- Used to identify certain gene mutations (single nucleotide polymorphism or SNPs) which are expressed in an unfavorable lifestyle environment.*
- SNP intervention is used to successfully treat gene mutations with lifestyle changes, proper nutrition and phytonutrients supplementation.*
- Modern genomics is based on personalised prevention. Although usually used to stop the development of age related degenerative diseases, prevention is recommended for young and old, and it is never too early to start.*
Dr. Sly Nedic is an anti-aging diplomat (board certified by WOSAAM) and is on the advisory board for Genetic Testing at Laboratory Reunis Luxembourg. She provides genetic counselling and personalised life style changes in a scheduled consultation both locally or oversees, with a possibility of a Skype consultation.
Genetic Tests Available:
- WEIGHT Gene and risk assessment for OBESITY
- INSULIN resistance and DIABETES TYPE 2
- Sporadic BREAST cancer and ESTROGEN metabolism
- COLON cancer
- Risk assessment PROSTATE cancer
- Risk assessment for HEART ATTACK
- Risk assessment for Female HORMONE replacement therapy
- ALZHEIMER’S & PARKINSON’S disease
- DETOXIFICATION capacity & OXIDATIVE STRESS
- LIPID METABOLISM
- Risk assessment for OSTEOPOROSIS
- ANDROGENIC ALOPECIA (male hair loss)
- SKIN health & DENTAL health (periodontitis)
- NICOTINE addiction gene
- WELL-BEING test (Testing 90 genes including Neurotransmitters, Inflammations mediators, Stress genes, Coagulation, Anabolism & Catabolism, etc.)
- CROHN’S disease
- AUTISM gene
If there is a family history or you think you are prone to any of the diseases or cancers that are not listed, please contact us on 011 884 6418 or email 8th Sense for further assistance.
Weight Loss & Personalised Nutrition
Every year there is a new diet in circuit, which often works for some individuals but not for others. Furthermore, obesity, insulin resistance and the inability to lose stubborn fat has reached epidemic proportions world wide and in South Africa. Many individuals complain that they can not lose weight despite caloric and carbohydrate restrictions and dedicated exercise.
What can be a reason for this inability to lose stubborn fat?
- Hormonal problems: hypothyroidism, altered Cortisol level due to ongoing stress, Estrogen dominance, low Testosterone, low Growth hormone etc.
- Environmental toxicity functioning as endocrine disruptors in which case bodies’ detoxification capacity is decreased leading to Insulin resistance
- Situation in which an individual is overwhelming metabolic pathways with too much sugar – usually hidden or not perceived as too much carbohydrate.
- Underlying medical problems as leaky gut syndrome, Cushing disease, Depression etc.
Genetic predisposition: presence of FAT genes leading to for example Leptin resistance, genes for Insulin resistance and Diabetes type 2, genes involved in inability to metabolize saturated fat (in which case high fat diet will not work), genes involved in high inflammation etc.
In a very simplified way individuals with an “apple shaped” body (stubborn tummy fat) have high incidence of Insulin resistance, Diabetes type 2 and low testosterone. Aditionally, those with a “pear shaped” body suffer from detoxification problems and Estrogen dominance. Generalized obesity is usually more prominent in individuals who have Leptin resistance and Fat genes. However, in order to categorically uncover the underlying condition, patients need medical screening, genetic testing and thorough personal Q&A about diet, nutrition and life style habits.
8th Sense offers personalised nutrition for long term weight loss and reversal of Insulin resistance. The client will be informed about unique genetic make-ups that can create risks with certain environmental factors. Blood testing results, lifestyle choices and environmental influence will be considered and used to create a tailor-made solution for each individual patient.*
Contact us for further assistance on 011 884 6418 or email 8th Sense .
Stressful modern-day lifestyle, environmental toxicity, electromagnetic radiation, depleted nutrition and many other factors are challenging both the young and the old. As a consequence, there’s an immense amount of people out there who are unwilling to wait for a disease to become apparent – they’re wise enough to search for a different, more preventive way to protect their health and well-being.
These factors have prompted a large number of medical professionals to look beyond conventional sickness-curing and examine a wider set of diagnostic approaches and health-maintaining methods. Many of those new ideas have influence the creation of Functional Medicine, Integrative Medicine and Preventative Medicine.
Major difference between conventional and Functional Medicine is in the way they approach health issues. Conventional medicine can often fall into the trap of treating the visible symptoms and insisting on a rigid, “one size fits all” solution. Functional Medicine, on the other hand, is striving to find the real root of the health imbalance while examining the patient’s unique psychology, lifestyle and environment.
Personalised Medicine Is a one step up from Functional Medicine. It uses Functional Medicine model tailored to each individual according the their own genetic make up. Dr. Nedic uses this approach for both the “Functional Medicine” cases (Chronic Fatigue, ME, Fibromyalgia, Insulin Resistance, Autoimmunity) and the “Anti-Aging and Regenerative Medicine” cases. It’s a tailored approach where each patient receives his own combination of supplements, lifestyle advice, nutrition programs and a customised exercise program.*
*Disclaimer: Treatment results will vary on a patient to patient basis. No guarantees can be made